|
KMID : 0605620100170010044
|
|
Journal of Korean Society of Biological Psychiatry
2010 Volume.17 No. 1 p.44 ~ p.48
|
|
|
Higher QT dispersion in patients with social anxiety disorder
|
|
Kwon Young-Do
Lim Se-Won
Oh Kang-Seob
|
|
|
Abstract
|
|
|
Objectives: Social phobia is frequently accompanied with autonomic nerve system symptoms. QT dispersion(QTd) is the maximum inter-lead difference in QT interval, an indicator of the autonomic nerve system(ANS) disparity of the heart itself. The objective of this study is to investigate the ANS disparity, which is measured by QTd, is associated with pathophysiology of social phobia.
Methods: This research have compared QT dispersion of 25 physically healthy social phobia outpatients(16 men, 9 women, the average age 35.5±12.9) and age and sex matched control group of mentally and physically healthy 25 volunteers(16 men, 9 women, the average age 34.83±12.7). QT dispersion was measured by previously described method.
Results: QT dispersion(QTd) and rate-corrected QT dispersion(QTcd) were significantly higher on the patients group than control group(QTd (patients vs. controls: 52.60±27.63ms vs. 27.53±14.29ms, P < 0.0001), QTcd (patients vs. controls: 55.79±27.98 ms vs. 29.10±14.24 ms, P< 0.0001)).
Conclusions: Our study showed that the patients with social phobia have higher QT dispersion than normal controls. These results suggest that the ANS disparity, which is measured by QTd, is associated with pathophysiology of social phobia..
|
|
|
KEYWORD
|
|
|
QT dispersion, Social phobia, Anxiety disorders, ECG, Autonomic nerve system
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|